Aurora Kinase A

An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION.

Also Known As:

AURKA; AURORA2 Protein; Aurora A Kinase; Aurora-A Kinase; AuroraA Kinase; BTAK Protein; Breast-Tumor-Amplified Kinase; STK15 Kinase; Serine-Threonine Protein Kinase 15; Breast Tumor Amplified Kinase; Serine Threonine Protein Kinase 15; Aurora A Kinases; Aurora Kinases A

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Transferases: 6719
    - Phosphotransferases: 43773
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9899
        Protein Serine-Threonine Kinases: 3707
        Aurora Kinases: 668
        Aurora Kinase A: 1107
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cell Cycle Proteins: 812
    - Aurora Kinases: 668
      - Aurora Kinase A: 1107
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3707
      - Aurora Kinases: 668
        Aurora Kinase A: 1107

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Disease

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